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Bupropion HCL
Category:- Antidepressant, Smoking cessation adjunct.
Description :
Bupropion (byoo-PROE-pee-on ) is used to relieve mental depression and is used as part of a support program to help you stop smoking.
Bupropion is sold under different brand names for different uses. If you are already taking medicine for mental depression or to help you stop smoking, discuss this with your health care professional before taking bupropion. It is very important that you receive only one prescription for bupropion at a time.
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Before Using This Medicine:-
In deciding to use Bupropion HCL, the risks of taking the medicine must be weighed against the good it will do. For Bupropion HCL, the following should be considered :
Allergies —Tell your doctor if you have ever had any unusual or allergic reaction to bupropion. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.
Pregnancy —Studies have not been done in pregnant women. Bupropion has not been reported to cause birth defects or other problems in animal studies. Before taking this medicine, make sure your doctor knows if you are pregnant or if you may become pregnant.
Breast Feeding —Bupropion passes into breast milk. Because it may cause unwanted effects in nursing babies, use of bupropion is not recommended during breast-feeding.
Children —This medicine has been tested in a very small number of patients 6 to 16 years of age and has not been shown to cause different side effects or problems in children than it does in adults. More testing is needed to decide whether bupropion is safe and effective for use in children.
Older Adults —This medicine has been tested in a limited number of patients 60 years of age and older and has not been shown to cause different side effects or problems in older people than it does in younger adults.
Other medicines —Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking bupropion, it is especially important that your health care professional know if you are taking any other Medications.
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Other medical problems :—
The presence of other medical problems may affect the use of Bupropion HCL. Make sure you tell your doctor if you have any other medical problems, especially:
- Anorexia nervosa, or history of or
- Brain tumor or
- Bulimia, or history of or
- Drug abuse or
- Head injury, history of or
- Mental retardation or
- Seizure disorders
- Sudden stop in drinking alcohol or using sedatives (medicine that makes you sleepy) or benzodiazepines (alprazolam [e.g., Xanax], diazepam [e.g., Valium], triazolam [e.g., Restoril])
The risk of seizures may be increased when Bupropion HCL is taken by patients with these conditions
- Bipolar disorder (manic-depressive illness) or risk of or
- Other nervous, mental, or emotional conditions or
- High blood pressure—Bupropion may make the condition worse
- Heart disease—Higher blood levels of bupropion may result, increasing the chance of side effects, or blood pressure may be increased
- Kidney disease or
- Liver disease—Higher blood levels of bupropion may result, increasing the chance of side effects
Proper Use of Bupropion HCL:-
Use bupropion only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may increase the chance of side effects.
For patients taking the prompt-release tablet form of this medicine
- Take doses at least 4 hours apart to decrease the chance of seizures.
For patients taking the sustained-release tablet form of this medicine
- Take doses at least 8 hours apart to decrease the chance of seizures.
- Swallow tablets whole. Do not crush, break, or chew them.
For patients taking the extended-release tablet form of this medicine
- Take doses at least 24 hours apart to decrease the chance of seizures.
- Swallow tablets whole. Do not crush, break, or chew them.
To lessen stomach upset, this medicine may be taken with food, unless your doctor has told you to take it on an empty stomach.
For patients taking this medicine for mental depression
- Usually Bupropion HCL must be taken for several weeks before you feel better. Your doctor should check your progress at regular visits.
- You will probably need to keep taking bupropion hcl for at least 6 months to help prevent the return of the depression.
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Dosing :—
The dose of bupropion hcl will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of bupropion. If your dose is different, do not change it unless your doctor tells you to do so.
The number of tablets that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are taking bupropion.
Missed dose :—
If you are taking the extended-release or the prompt-release form of this medicine and you miss a dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Storage :—
To store this medicine :—
- Keep out of the reach of children.
- Store away from heat and direct light.
- Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down.
- Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.
Precautions While Using Bupropion HCL :-
Your doctor should check your progress at regular visits, especially during the first few months of treatment with this medicine. The amount of bupropion hcl you take may have to be changed often to meet the needs of your condition and to help avoid unwanted effects.
Do not take bupropion within 14 days of taking an MAO inhibitor.
Drinking of alcoholic beverages should be limited or avoided, if possible, while taking bupropion hcl. This will help prevent seizures.
Bupropion HCL may cause some people to feel a false sense of well-being, or to become drowsy, dizzy, or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert and clearheaded.
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Side Effects of Bupropion HCL :-
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
- Agitation; anxiety
- Buzzing or ringing in ears; headache (severe); skin rash, hives, or itching
- Confusion; extreme distrust; fainting; false beliefs that cannot be changed by facts; hallucinations (seeing, hearing, or feeling things that are not there); seizures (convulsions), especially with higher doses; trouble in concentrating.
Incidence not determined:-
- Actions that are out of control; anger ; assault; attack; being impulsive; chest pain or discomfort ; fast or pounding heartbeat; force; inability to sit still; irritability; need to keep moving; nervousness; restlessness; sweating; talking, feeling, and acting with excitement
- Symptoms of overdose--may be more severe than side effects seen at regular doses, or two or more may occur together
- Fast heartbeat; hallucinations (seeing, hearing, or feeling things that are not there); loss of consciousness ; nausea; seizures (convulsions) ; vomiting
Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:
- Abdominal pain; constipation; decrease in appetite; dizziness; dryness of mouth; increased sweating ; nausea or vomiting; trembling or shaking; trouble in sleeping; weight loss (unusual)
- Blurred vision; change in sense of taste ; drowsiness; feeling of fast or irregular heartbeat; frequent need to urinate ; muscle pain; sore throat ; unusual feeling of well-being
Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.
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